Scientists Uncover Genes That Could Explain Why Humans And Labradors Get Obese!
Researchers have uncovered important genetic links between scientist British Labrador retrievers and human obesity. A study has revealed that certain genes in dogs, specifically the DENND1B gene, contribute to obesity in both dogs and humans. This groundbreaking research could open new doors in understanding how genetic factors influence appetite and body weight in humans.
Genetic Discovery in Dogs
The study, conducted by researchers from the University of Cambridge, focused on Labrador retrievers, a breed prone to obesity. They found that the DENND1B gene was most strongly linked to canine obesity. This gene plays a role in regulating the body’s energy balance through the leptin melanocortin pathway in the brain. Interestingly, humans also carry this gene, and it is similarly associated with obesity.

In addition to DENND1B, four other genes linked to canine obesity were identified, though their effects were smaller. These genes also have connections to human obesity, which highlights the similarities between the two species when it comes to weight regulation.
How Genetics Influence Appetite
Researchers discovered that dogs with a high scientist genetic risk for obesity were more likely to have a strong appetite. These dogs showed a greater tendency to beg for food and were less selective eaters. This finding parallels obesity, where people with high genetic risk often struggle with overeating and weight gain unless they make significant efforts to control their diet and exercise.

Preventing Obesity with Control and Effort
While genetics play a significant role in obesity, the scientist study also revealed that strict diet and exercise can prevent obesity, even in dogs with a high genetic predisposition. Similarly,who are genetically at risk can manage their weight through healthy lifestyle choices, though it requires more effort and discipline.
Can Dogs Help Us Understand Human Obesity?
The researchers emphasized that studying dogs provides valuable insights into human obesity. Dogs share similar environmental factors with humans, such as diet and lifestyle, and their high genetic similarity within a breed makes it easier to link specific genes to obesity.
This scientist study also sheds light on how the brain controls appetite and energy use. By understanding these genetic factors, researchers hope to develop better treatments for obesity in both dogs and humans.

Practical Tips for Dog Owners
For pet owners, the scientist study suggests ways to manage their dogs’ appetite. Using puzzle feeders or spreading out food can help keep dogs distracted and prevent overeating. Choosing more satisfying food options can also help manage their hunger and prevent obesity.
This research highlights the powerful connection between human and canine genetics, paving the way for future advancements in understanding and treating obesity.